I can't speak for the Titan, but there has been nothing wrong with my uncle's 2010 Tundra and he's far from a perfect owner.

Conversely, my dad's '05 Silverado 2500 Duramax that has less than 50K on it has gone through 2 intermediate steering shafts, has thin sheet metal along the bed rails that dents VERY easily, and has absolutely terrible interior quality. The plastics are all junk and the lower dash rattles like heck over any bump. The "leather" is actually vinyl, so GM should very well be sued for lying. The power extendable tow mirrors won't extend anymore, which is a hugely common issue on these trucks. My Grandpa's 04 Sierra which is the same mechanically also has the failing mirrors and the symptoms of the ISS clunk...with 32K. Did I mention the Silvy cost $47K new? The only reason he bought this truck was because Toyota doesn't have a Diesel. His '01 Tundra Limited was a better truck in every way, and cost less. The "issues" with the Tundra are overblown. My Grandpa also has a '95 T100 that he will not sell that has held up absolutely perfectly over the past 16 years.

There's a reason why the rest of the world laughs at the trucks sold in the US.