jehmin

ES300 2000
Wont Move or Roll in Neutral.
Brakes don't seem to be the issue
Minus the E Brake which wasn't checked
Front Wheels will turn slowly when lifted in the air and not grounded.
Trans Seems to be shifting judgeing by sounds. Fluid is a little dark but level should be ok.
Axle is not busted- actually changed this part thinking this was the issue.There is some resistance spinning front wheel will driver side with car off ground.
Passenger Axle will spin nicely if the driver side axle isn't attached.

Any Ideas?

Oro

Does it do this with the calipers fully removed? If not, or it was not checked that way:

Pull the caliper pins on the driver side axle and see if the wheel spins more freely. If so, clean them very thoroughly and the cavities, and then re-grease with silicone grease. Then do all the others. Make sure the pin hats are all in good shape and replace if needed.

Alternatively, after driving it stop and go a little while, touch all the wheel hubs and see if one or more are much hotter than the rest.

jehmin

Havent checked with calipers removed. When in drive and car lifted in air and when the wheels spin, pressing the brakes will stop the turning.
The wheels seem to turn with axle out and calipers on. Resistance is experienced with axle back into the wheel hub.
WIll have to double check these details as this is all from memory

ArmyofOne

Sounds like your differential is gone (its in the transaxle case).