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I've seen several GS with 22's in person and I didn't like any of them. 22's are too big for the GS. 21 might be alright and I'll emphasize the word might. 22 are definitely a no go.
I wonder if the OP is going to whine about ride comfort... we have people who moved up to 19s and 20s that whine and whine all day about its too rough and so on.