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I'm certainly no expert on the IS300 engine. But a "wet" kit with a window switch trigger is probably a good (safe) place to start. If you're unfamiliar with nitrous set-ups, do some research first. There's plenty of information on manufacturer websites such as Zex.
Ya ,you can its the same set up as a is250 . Just use the 7th cold start fuel inj. Fuel line and T in to the system for a wet kit. If u need so help pm ive done a some kits for my bros