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for the record lexus cars are very sensitive to wheel balance and alignment (pretty well known "issue"). i had vibration before as well, but since i carefully balanced the wheels, etc... i have 20s on both my gs400 and sc430 and no vibrations at all at any speed
Took my wheels in today to have Force Balanced at a shop in Simi Valley. The roller found one of the rims had a small inside dent. The vibration is now gone but I have a spare wheel that is going on shortly.
They charged me $17.50 each wheel.